When dealing with advanced layout features, it makes sense to place all of your CSS inside of a feature query, including media queries for the advanced layout. However, Chrome (currently) drops the ball on that last part.

TL;DR: You currently can’t quite nest media queries inside feature queries in Chrome, but the other way around is fine. This bug has since been fixed, and should go away in upcoming versions of Chrome.

Read the whole post "Enquire Within Upon @media"